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Fundamental - Factsheet

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KARYOPHARM THERAPEUTICS INC KARYOPHARM THERAPEUTICS
Updated on 27 Jan 2020 (End of trading day)
Last (USD): 15.875 Change: -0.625 High: 16.440 Remarks: -
Change (%): -3.79 Low: 15.770
Open 15.890 Yesterday's Close 16.5
Buy Price - Sell Price -
Buy Volume (share) - Sell Volume (share) -
Cumulative Volume (share) 875,844 Cumulative Value
Click to show Stock Prices chart

Key Statistics

EPS (USD) a -2.84133 Trailing EPS (USD) e -3.33099 NAV (USD) b 0.9535
PE a - Trailing PE f - Price / NAV b 16.6492
Dividend (USD) d - Cash In Hand (USD) g 2.6756 Issued & Paid-up Shares c 62,790,000
Dividend Yield (%) d - Price / Cash In Hand g 5.933 Treasury Shares h -
Beta - 75 Daysi 2.216 R-Squared - 75 Days(%)i 8.59 Market Cap (M) 996.791
Beta - 500 Daysi 0.124 R-Squared - 500 Days (%)i 0.09 Enterprise Value (M) 852.450
Piotroski F Score 2 Exchange Code KPTI Par Value ( $ ) n.a.
52 Weeks Volatility (%) 93.60 Free Float (%) 88.6
Sector & Industry Health Technology - Biotechnology
Notes:
  1. Based on latest Full Year results announcement, adjusted for the current number of shares.
  2. Based on latest results announcement (Full Year, Half Year or Interim), adjusted for carrying value of "Other Share Capital", illustrative financial effects of corporate actions (if applicable) and the current number of shares.
  3. Rounded to the nearest thousand. Updated on 05 Nov 2019.Please click here for more information.
  4. Dividend is based on latest Full Year results announcement, adjusted for current number of shares and excludes special dividend.
  5. Summation of the earnings from the latest 4 Quarter (or 2 Half Year) results announcement, adjusted for the current number of shares.
  6. Based on Trailing EPS.
  7. Based on reported cash and cash equivalents at end and extracted from the latest results announcement (Full Year, Half Year or Interim), adjusted for the current number of shares.
  8. Rounded to the nearest thousand. Updated on 13 Jul 2015.
  9. Beta and R-Squared are calculated in relation to the market index using the historical daily closing values of the stock and index as data points.

Peer Comparison

Type Name Market Market Cap (M)a PE b Trailing PE c Price / NAV d Dividend Yield (%)d
Reference KARYOPHARM THERAPEUTICS INC NASDAQ 996.791 - - 16.6492 -
Industry Biotechnology NASDAQ 2,320.557 357.556 92.382 5.7714 0.764
Local Peer AMGEN INC NASDAQ 132,473.323 15.782 16.422 12.1235 2.509
Local Peer GILEAD SCIENCES INC NASDAQ 80,754.524 14.804 29.987 3.9194 3.620
Local Peer VERTEX PHARMACEUTICAL NASDAQ 58,468.196 27.890 27.274 11.1296 -
Local Peer BIOGEN INC NASDAQ 50,729.464 11.450 9.402 3.6246 -
Local Peer ILLUMINA INC NASDAQ 46,146.240 55.867 47.427 10.3956 -
Local Peer REGENERON PHARMACEUTICALS INC NASDAQ 37,266.948 15.246 17.380 3.5477 -
Local Peer ALEXION PHARMACEUTICAL INC NASDAQ 23,301.942 300.282 15.848 2.2477 -
Local Peer SEATTLE GENETICS INC NASDAQ 18,926.156 - - 10.6350 -
Local Peer INCYTE CORPORATION NASDAQ 16,385.250 149.647 40.461 6.7637 -
Local Peer BIOMARIN PHARMACEUTICAL NASDAQ 15,199.868 - - 4.9440 -
Local Peer GALAPAGOS NV SPON ADR REPR 1 ORD SHS NASDAQ 14,696.869 - 47.354 5.3173 -
Local Peer ALNYLAM PHARMACEUTICALS INC NASDAQ 13,047.675 - - 8.1189 -
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Global Peer CSL ASX 141,910.746 52.894 52.894 18.9640 0.849
Global Peer AMGEN-T HKEx 594,184.000 9.032 9.399 6.9364 4.385
Global Peer AGILENT TECHNOLOGIES INC NYSE 26,849.440 84.967 25.070 5.6549 0.706
Global Peer SINO BIOPHARM HKEx 143,847.408 13.425 13.933 4.2839 0.640
Global Peer WUXI BIO HKEx 134,349.414 179.875 140.620 13.8295 -
Global Peer BEIGENE HKEx 100,670.850 - - 10.0445 -
Global Peer Lonza SGX 5,937.453 6.613 6.613 0.6568 4.787
Global Peer GENSCRIPT BIO HKEx 33,091.696 199.005 - 9.3319 -
Global Peer 3SBIO HKEx 27,939.670 18.469 22.480 2.7538 -
Global Peer EMERGENT BIOSOLUTIONS INC NYSE 2,763.949 44.082 642.779 2.6705 -
Other Global Peers ALPHAMAB-B (HKEx), HAOHAI BIOTEC (HKEx), POLYNOVO LIMITED (ASX), MYOVANT SCIENCES LTD (NYSE), MESOBLAST LTD (ASX), FRONTAGE (HKEx), CKLIFE SCIENCES (HKEx), NANOVIRICIDES INC (NYSE American), AVITA MEDICAL LTD (ASX), VIVA BIOTECH (HKEx), ASCENTAGE-B (HKEx), KADMON HLDGS INC (NYSE), SINOMAB BIO-B (HKEx), ARCUS BIOSCIENCES INC (NYSE), ASCLETIS-B (HKEx), ESSEX BIO-TECH (HKEx), LEE'S PHARM (HKEx), DPHARMA (Bursa), NEXT SCIENCE LTD (ASX), PFENEX INC (NYSE American), TELIX PHARMACEUTIC (ASX), BBI LIFE SCI (HKEx), NAVIDEA BIOPHARMACEUTICALS INC (NYSE American), NEUREN PHARMACEUTICALS LTD (ASX), LINEAGE CELL THERAPEUTICS INC (NYSE American), MATINAS BIOPHARMA HOLDINGS INC (NYSE American), UNI-BIO GROUP (HKEx), RESAPP HEALTH LIMITED (ASX), CEL-SCI CORP (NYSE American), PYC THERAPEUTICS LIMITED (ASX), ENZO BIOCHEM INC (NYSE), 22ND CENTURY GROUP INC (NYSE American), PALATIN TECHNOLOGIES INC (NYSE American), IMUGENE LIMITED (ASX), CYNATA THERAPEUTICS LTD (ASX), IMMUTEP LTD (ASX), ONCOSIL MEDICAL LIMITED (ASX), SYNTHETIC BIOLOGICS INC (NYSE American), ORTHOCELL LIMITED (ASX), CT ENTERPRISE (HKEx), ISORAY INC (NYSE American), INVEX THERAPEUTICS LTD NPV (ASX), BIOSINO BIO-TEC (HKEx), BIOTRON (ASX), GENETIC TECHNOLOGIES (ASX), KAZIA THERAPEUTICS LIMITED (ASX), ACTINOGEN MEDICAL LTD (ASX), ARMATA PHARMACEUTICALS INC (NYSE American), REGENT PACIFIC (HKEx), ANTEOTECH LIMITED (ASX), BIONOMICS LTD (ASX), MEMPHASYS LTD (ASX), TALI DIGITAL LIMITED (ASX), IBIO INC (NYSE American), EXTRAWELL PHAR (HKEx), CCP TECHNOLOGIES LTD (ASX), ORAGENICS INC (NYSE American), RHINOMED LIMITED (ASX), INDIA GLOBALIZATION CAPITAL INC (NYSE American), ACTINIUM PHARMACEUTICALS INC (NYSE American), PROTEOMICS INTL LABORATORIES LTD (ASX), IMMURON LIMITED (ASX), PRESCIENT THERAPEUTICS LIMITED (ASX), CELLMID LIMITED (ASX), PATRYS LIMITED (ASX), Suntar Eco-City^ (SGX), CONTANGO ASSET MANAGEMENT LIMITED (ASX), REGENEUS LTD (ASX), ADALTA LTD (ASX), ALTERITY THERAPEUTICS LIMITED (ASX), HOLISTA COLLTECH LIMITED (ASX), ANATARA LIFESCIENCES LTD (ASX), SIENNA CANCER DIAGNOSTICS LTD (ASX), NOVABAY PHARMACEUTICALS INC (NYSE American), CAN FITE BIOPHARMA LTD SPON ADS EA REP 30 ORD SHS(POST REV SPL (NYSE American), NEUROSCIENTIFIC BIOPHARMA LTD (ASX), AIM IMMUNOTECH INC (NYSE American), LIVING CELL TECHNOLOGIES (ASX), HAO WEN HLDGS (HKEx), BENITEC BIOPHARMA LTD (ASX), AUSTRALIAN PRIMARY HEMP LTD (ASX), BIOXYNE LIMITED (ASX), MEDIBIO LIMITED (ASX), QT Vascular (SGX), MGRC (Bursa), TBG DIAGNOSTICS LTD (ASX), AVECHO BIOTECHNOLOGY LTD (ASX), NANOLLOSE LTD (ASX), AMPLIA THERAPEUTICS LTD (ASX), BPH ENERGY LIMITED (ASX), FACTOR THERAPEUTICS LIMITED (ASX)
Notes:
  1. For companies, Market Cap is based on the trading currency of the company. Industry/Index Market Cap is the average market cap for that industry/index.
  2. Industry/Index PE is calculated using (Total Market Cap/Total Earnings) of all companies in the industry/index.
  3. Industry/Index Price/NAV is calculated using (Total Market Cap/Total Shareholders' Equity) of all companies in the industry/index.
  4. Industry/Index Dividend Yield is calculated using (Total Gross Dividend/Total Market Cap) of all companies in the industry/index.
  5. For Industry/Index calculation, data for foreign currency denominated companies will be converted to the main market currency using the latest exchange rate.
  6. Industry/Index/Peers data is updated daily.
  7. Peers are sorted by market capitalisation and only details for the top 10 will be shown.

Total Shareholder Return

PeriodDividend ReceivedCapital AppreciationTotal Shareholder Return
Short Term Return 5 Days --1.665
-9.49 %
10 Days --2.005
-11.21 %
20 Days --3.295
-17.19 %
Medium Term Return 3 Months -+4.355
+37.80 %
6 Months -+6.995
+78.77 %
1 Year -+7.635
+92.66 %
Long Term Return 2 Years -+3.885
+32.40 %
3 Years -+5.525
+53.38 %
5 Years --10.985
-40.90 %
Annualised Return Annualised --
-9.98 %
Notes:
  1. Total Shareholder Return (TSR) combines share price appreciation and dividends paid to show the total return to the shareholder expressed as a percentage.
  2. Script dividends are ignored in this calculation.

Price Movements

1 Year Range 3.920 - 20.090 Change From 1 Year Low +11.955 % Change From 1 Year Low (%) +304.97
Change From 1 Year High -4.215 % Change From 1 Year High (%) -20.98
2 Years Range 3.920 - 21.710 Change From 2 Years Low +11.955 % Change From 2 Years Low (%) +304.97
Change From 2 Years High -5.835 % Change From 2 Years High (%) -26.88
5 Years Range 3.920 - 35.650 Change From 5 Years Low +11.955 % Change From 5 Years Low (%) +304.97
Change From 5 Years High -19.775 % Change From 5 Years High (%) -55.47
Notes:
  1. Price movements are based on adjusted historical data.

Company Background

Karyopharm Therapeutics, Inc. is an oncology-focused pharmaceutical company dedicated to the discovery, development, and commercialization of novel first-in-class drugs directed against nuclear export and related targets for the treatment of cancer and other major diseases. Its SINE compounds function by binding with and inhibiting the nuclear export protein XPO1 (or CRM1). Karyopharm's lead compound, XPOVIOTM (selinexor), received accelerated approval from the FDA in combination with dexamethasone as a treatment for patients with heavily pretreated multiple myeloma. A Marketing Authorization Application for selinexor is also currently under review by the European Medicines Agency (EMA). In addition to single-agent and combination activity against a variety of human cancers, SINE compounds have also shown biological activity in models of neurodegeneration, inflammation, autoimmune disease, certain viruses and wound-healing. Karyopharm has several investigational programs in clinical or preclinical development. The company was founded by Joseph Araujo, Ronald A. DePinho, Pamela A Silver, Giulio Draetta, Michael G. Kauffman and Sharon Shacham on December 22, 2008 and is headquartered in Newton, MA.

Historical Price Data

Date Open High Low Close Volume VWAP
27 Jan 2020 15.890 16.440 15.770 15.875 875,844 -
24 Jan 2020 17.400 17.540 16.450 16.500 1,518,887 -
23 Jan 2020 17.150 17.520 16.835 17.340 860,006 -
22 Jan 2020 17.540 18.110 17.110 17.220 1,663,073 -
21 Jan 2020 16.930 17.690 16.780 17.540 1,390,180 -
17 Jan 2020 18.440 18.890 16.980 17.040 2,596,980 -
16 Jan 2020 18.550 19.100 18.370 18.830 758,336 -
15 Jan 2020 18.000 18.450 17.560 18.400 1,861,995 -
14 Jan 2020 17.350 18.030 17.000 17.880 988,046 -
13 Jan 2020 18.460 18.840 17.100 17.240 1,783,468 -
10 Jan 2020 19.160 19.500 18.350 18.375 1,158,097 -
09 Jan 2020 18.980 20.090 18.885 19.215 1,494,243 -
08 Jan 2020 18.510 18.869 18.300 18.620 869,878 -
07 Jan 2020 18.440 18.500 17.960 18.455 686,739 -
06 Jan 2020 17.840 18.540 17.260 18.470 1,345,301 -
03 Jan 2020 18.160 18.640 18.050 18.220 730,195 -
02 Jan 2020 19.280 19.400 18.080 18.720 1,124,881 -
31 Dec 2019 18.830 19.610 18.690 19.170 735,204 -
30 Dec 2019 19.250 19.520 18.830 18.940 678,680 -
27 Dec 2019 20.000 20.000 18.790 19.250 818,975 -
26 Dec 2019 19.500 19.920 19.310 19.665 1,095,581 -
24 Dec 2019 19.190 19.720 19.085 19.590 776,485 -
Summary
Current 2 Weeks
(13 Jan 2020 to 27 Jan 2020)
18.460 19.100 15.770 15.875 14,296,815 -
Previous 2 Weeks
(27 Dec 2019 to 10 Jan 2020)
20.000 20.000 15.770 18.375 9,642,193 -
4 Weeks from
(27 Nov 2019 to 26 Dec 2019)
16.870 19.100 15.770 19.665 27,133,136 -
View All Historical Data

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